CBD is one of over 100 cannabinoids that are present in Cannabis. There are different forms of Cannabis plants, which include Cannabis Sativa and Indica. For most folks they are familiar with the term marijuana and hemp. The primary difference is the amount of THC, primarily delta 9 THC, in the plant. For the purpose of this review we are referring to CBD that is found in Hemp, which is a Cannabis plant that naturally produces low concentrations of Delta 9 THC, less the 0.3%, and is federally legal to grow and cultivate. The most recent Hemp Farm Bill of 2018 made Hemp federally legal.

There are over 100 different cannabinoids in the Cannabis plant. The two most prevalent cannabinoids are THC and CBD. Remember that the Hemp plant produces very little THC, thus we get mostly CBD from the Hemp plant. The importance of the difference between CBD and THC is that THC, mainly delta 9 THC, can be psychoactive and makes you high. CBD does not have any psychoactive effects and can help reduce the psychoactive effect of THC. Other cannabinoids include CBG, CBN, CBC, THCV. We will discuss other cannabinoids later. We have learned much about CBD and other cannabinoids over the past several years, with an increasing number of clinical and scientific literature supporting the benefits of CBD and other cannabinoids. We aim to offer Tinctures and Gummies with specific cannabinoid and terpene profiles.

The cannabinoids that are found in Cannabis are phytocannabinoids, which means they come from plants. Our body produces cannabinoids on its own, and there is a robust cannabinoid receptor system in the human body, this is called the ECS [endocannabinoid system]. It the most prevalent receptor system in the human body, thus the wide range of benefit we see from CBD and other cannabinoids. The two identified cannabinoid receptors that have been studied are CB1 and CB2. They are located in different places in our body and impart a different action when activated. We will discuss the ECS later. There are also many other areas in the body and central nervous system where CBD interacts. Different receptors include 5HT, adenosine, glycine and GPR55 among others. You may recognize some of these receptors because many of the medication you take are designed to work at the same sites.

The Endocannbinoid System

CBD and the ECS plays a role in regulating many physiologic processes in the human body. Basically, when things are not in balance, the ECS system works to get things back in balance. The result of an endocannabinoid system that does not function properly is disease. It is suspected that for some their ECS may not be working properly or may have a deficiency in one of the chemicals by which CBD works, anandamide. Thus, supplementing the ECS with an external source of cannabinoids like CBD can help with many symptoms. The details of the mechanism of actions is too complicated for this review but we will provide links to medical literature for more details for those who wish to do a deep dive.

One of the useful effects of CBD is that it can block some of the negative effects of THC, notably the psychoactive effects. In addition, CBD interaction at different receptor sites results in the ability of CBD to help manage symptoms with many different conditions. Our CBD products, tinctures, gummies, gel caps and topicals are developed to help manage your symptoms associated with many different conditions.

These conditions include

  • Mood disorders, such as anxiety and depression
  • Autoimmune diseases (inflammation and arthritis)
  • Pain conditions, chronic pain.
  • Gut issues, such as Crohn’s Disease, Colitis and IBS.
  • Neuroprotection, Parkinson’s Disease, Multiple Sclerosis, Epilepsy
  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684164/
  2. https://pubmed.ncbi.nlm.nih.gov/20565726/

Cancer

The takeaway here is that CBD can offer another option for folks who are looking for other options to manage ongoing symptoms and medical conditions. CBD is not a substitute for already approved treatments and medications. We recognize that there is a limited foundation and evidence to recommend CBD as a primary choice for therapy. It does have a place for many people who have failed other therapies and medications. Many available treatment options may have other adverse effects or may just not be well tolerated. It should be noted that CBD has been well recognized as safe with no evidence to suggest any lethal dosage. There are very few, if any, side effects.

CBD offers an effective, well-tolerated, and safe option for many who need the relief of many symptoms. We will provide additional information and education on CBD and specific evidence of its clinical benefits. Please come back to see more blogs on the benefits of CBD, and please try one of our products. Visit our SHOP page and look over our tinctures, gummies, gel caps and topicals. We can help you determine what is best for you.

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387667/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/